Clinical Users

Future-proof in everyday clinical practice

Bringing neuronavigation to the next level

Our view of progress is to make life as pleasant as possible for you and your patients. We support and accompany you as a partner at your side and adapt each system individually to your needs. Patients trust you when they know that they will receive tailor-made treatment at the highest level. In this way we create the best conditions for successful therapy.

TMS Navigator TS

Image-guided neuronavigation redefines the precision and effectiveness of TMS therapy. Infrared tracking ensures that every TMS impulse reaches the intended brain region – gold standard in TMS Navigation.

The Localite TMS Navigator TS significantly improves the key areas of planning, navigation, and documentation:

  • In planning, target areas where stimulation is to take place are precisely defined. Patients receive customized, focused treatments.
  • During navigation, real-time tracking feedback empowers the user to place the TMS coil with maximum precision and directly control the accuracy of each pulse delivered.
  • In terms of documentation, the system meticulously records each TMS pulse relative to the target, enabling robust post-hoc quality assessments and providing confidence in treatment outcomes.

Use Cases

The best we can do for our most precious organ

Image-guided neuronavigation for TMS therapy opens up new possibilities in both psychiatric and neurosurgical applications. For the treatment of mental conditions such as depression , obsessive-compulsive disorder (OCD) and addictions, it enables clinicians to precisely target and stimulate specific brain regions, increasing both efficacy and patient experience.

Additionally, neuronavigation serves as a valuable tool in presurgical mapping for brain tumor resection, supporting surgeons in identifying critical brain areas to minimize functional impairment due to surgery.

TMS Navigator Variants

Localite’s therapeutical systems, the FDA-cleared TMS Navigator TS and TS+, are the ideal solution for implementing customized TMS treatment plans. The gold standard optical tracking technology, trusted by many advanced applications, offers exceptional accuracy for TMS navigation. Select from two different tracking camera sizes to fit your treatment environment seamlessly

  • TMS Navigator TS, featuring the NDI Polaris Lyra
  • TMS Navigator TS+, featuring the NDI Polaris Vega

Combined with the mobile system cart to effortlessly move the navigation system into position when and wherever it is needed, the TMS Navigator TS and TS+ are the optimal companions to any TMS treatment setup. On the software side, the TMS Navigator TS and TS+ can be individually configured to work with a wide range of image data, from the standard MNI template to individual MRI datasets (DICOM, NIfTI, Analyze) up to functional data (fMRI, PET/SPECT).

Structured step-by-step wizards, which can be accessed hands-free using the foot switch, support the operator in core functions such as patient registration and TMS coil navigation. The unique bi-directional connection to MagVenture stimulators further eases the workflow when using MagVenture equipment by automatic coil detection, transfer of MEP data to trigger markers during motor threshold hunting, and the ability to elicit TMS pulses via the navigation interface or foot switch.

Cost-effective and intuitive without compromising on precision: The TMS Navigator TS MR-Less offers the ideal entry into image-guided TMS navigation. Here as well, we rely on the trusted gold standard optical tracking. Designed for ease of use, it utilizes the MNI standard brain template.

This allows TMS sessions to be planned and conducted quickly without the preliminary step of creating individual MRI scans. Therefore, this edition is perfect for clinics seeking a standardized, efficient approach for TMS therapy for conditions such as depression or OCD. It is attractive for both novice and experienced practitioners.

The TMS Navigator TS MR-Flex takes TMS therapy to a new level. By integrating individual MRI data such as NIfTI and DICOM formats, it elevates treatment planning and the navigation process.

This personalized approach enhances targeting accuracy by tailoring interventions to each patient’s unique neuroanatomy. Trusted gold standard optical tracking is complemented by patient-specific imaging, creating a powerful tool for effective, customized TMS therapy.

The most advanced variant of our TMS Navigator TS. Inspired by Stanford University’s SAINT approach, it combines template-based targeting (MNI brain atlas), customized MRI-based navigation, and high throughput capabilities. The SAINT studies (1, 2) were conducted with the TMS Navigator proving its reliability in delivering accelerated TMS therapy for psychiatric conditions.

Designed for clinics with high patient volumes, the SNT-ready system features an additional head tracker, significantly reducing setup time and ensuring seamless transitions between patients. In addition, it allows the import of functional imaging data (fMRI, PET, etc.), enabling a truly personalized treatment by targeting a patient’s brain regions based on their individual brain activity patterns.

Gold-standard optical tracking, streamlined workflows, and individualized treatment capabilities: The TMS Navigator TS SNT-ready offers the ultimate solution for practitioners seeking to combine efficiency, precision, and clinical excellence in TMS therapy.

Regulatory affairs

In the EU, Localite TMS Navigator products and accessories are CE marked medical devices.

In the U.S., only Localite TMS Navigator TS is FDA cleared for following intended use:

The TMS Navigator TS helps users to plan, implement and document treatment involving TMS of the brain. The system provides planning and navigation functions using anatomical MR data. Regions of the brain to be stimulated can be determined on the basis of anatomy, functional areas or by entering previously calculated coordinates from brain atlases.

The product is intended for use with the MagVenture therapy systems supplied by Tonica Elektronik A/S (Farum, Denmark), more precisely the R20 and R30 stimulators, the R30 TMS stimulator with MagOption, the X100 stimulator and the X100 stimulator with MagOption only with following magnetic coils: C-100, C-B60, Cool-B65, Cool-B70, Cool D-B80, MC-125, MC-B70, MCF-75, MCF-125, MCF-B65 and MMC-140-II.

Integrated solutions

Perfect team play leads to results

Testimonials

Voices about our work

Reliable neuronavigation of the TMS coil, preferably based on individual MRI scans, is a key requirement for state-of-the-art therapeutic approaches. The possibility to further account for functional brain imaging information and personalized electric field simulations brings targeting accuracy to the next level.

Prof. Dr. Til Ole Bergmann | Acting Director NeuroImaging Center (NIC), University of Mainz

Prof. Dr. Til Ole Bergmann

Localite has proven to be an excellent partner in the field of navigated transcranial magnetic stimulation. Their dedication to quality and accuracy is of highest importance for precise and individualized brain stimulation. Our research combines various state-of-the-art brain stimulation and mapping approaches. Localite has been very supportive over the years, accommodating their products to our unique needs.

Prof. Hartwig R. Siebner | Director, Danish Research Centre for Magnetic Resonance, Copenhagen

Prof. Hartwig Siebner

The best in class quality and FDA clearance of Localite’s navigation products instills trust in the SAINT neuronavigation technique.

Christian Gormsen | President and CEO of Magnus Medical, Burlingame

Christian Gormsen

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