Project Details

Personalized multi-target brain stimulation to restore brain function in treatment-resistant depression (Precision-BCT)

Precicion BCT

The aim of the project is to develop and commercialize a personalized brain stimulation therapy for major depressive disorder (MDD) that accurately targets individual dysfunctional brain circuits. By integrating functional brain imaging with multi-site transcranial magnetic stimulation (TMS), the project seeks to enhance the precision of treatment, offering improved clinical outcomes and fewer side effects compared to standard TMS protocols.

A key feature of the envisioned system and workflow is the use of real-time induced electric field (E-field) simulation integrated into Localite’s TMS Navigator software to optimize the delivered stimulation.

Once demonstrated in MDD, the approach may be applicable to other neuropsychiatric disorders, offering a more tailored therapeutic option.

Project Coordinator

Hartwig R. Siebner

Danish Research Centre for Magnetic Resonance (DRCMR)

Project budget

Funding amount overall network

DKK 14,2 Mio

Project duration

09/01/2019 – 10/31/2025

Sponsors

Innovation Fund Denmark

Project Consortium

Shaping meaningful innovation together

LOCALITE GmbH Partner Logo
DTU Health Technology
MagVenture
Center for Neuropsychiatric Depression Research (CNDR)
LMU Klinikums München

Other Projects

Research leading to results

  • Transcranial Magnetic Stimulation

    TMS-LOK

  • Transcranial Focused Ultrasound

    3MP-FUS