Researcher

Localite – your partner in research

Leading technology for leading research

It’s a bumpy road to knowledge. Research always means setting the highest standards for yourself, the project, and the equipment. Particularly in neuronavigation, you naturally expect the highest precision, reliability, and pleasant working conditions. Qualities the TMS Navigator offers you.

For more than twenty years, Localite has been supporting researchers worldwide with cutting-edge technology at the highest level. Our company’s roots lie in research, we cooperate with leading scientists.

That’s why we know what matters. With the TMS Navigator, we offer you precise navigation, high-quality support, and a modular system that is tailored meticulously to your needs. It combines intuitive operation with cutting-edge technology, you are always up to date with the latest upgrades. We do everything we can to ensure you have the ideal research conditions.

P.S.: You are curious about what research projects we are currently working on at Localite? We are happy to tell you more here.

Use Cases

Always the solution that fits you best

MR-Less Navigation

Even without anatomical image data, the TMS Navigator enhances targeting and reproducibility. In that case navigation is based on the MNI template, which is adapted to the patient’s individual head shape.

Focused Ultrasound

Localite is committed to staying at the forefront of transcranial brain stimulation advancements, actively developing navigation solutions for transcranial ultrasound stimulation (TUS). Don’t scratch just the surface: Our software navigates ultrasound transducers with the same ease as TMS coils.

Speak with our experts and explore our ongoing research projects (CITRUS, 3MP-FUS) to discover how Localite can support dual-use navigation for both TUS and TMS, expanding possibilities for researchers worldwide.

Functional Imaging Data

Don’t rely solely on structural images – integrate functional imaging data as well. Use fMRI to localize motor hotspots or analyze resting-state activation patterns in the dlPFC. By combining structural and functional data, researchers can apply more sophisticated and informed stimulation protocols than ever before.

Stimulation Export

Combine precise coil positioning with MEP stimulation responses. Map MEP responses or stimulator output onto the subject’s personal MRI to streamline motor threshold-hunting procedures and improve reproducibility.

Highly regarded by researchers in presurgical mapping and motor framework studies, the TMS Navigator brings a new level of precision and flexibility to the field.

EEG – TMS

Combine precise navigation of the TMS coil with accurate EEG electrode positioning. Boost reproducibility by comparing electrode positions between sessions. Derive exact coordinates for later use as covariates in more sophisticated EEG analysis. Navigate the TMS coil to exact electrode positions and enhance your stimulation outcome.

TMS Navigator Edition

Adapts to your demands

TMS Research value technology

TMS Navigator

Value Edition

The Value Edition empowers scientists with precise and reproducible navigation of their TMS coils, ensuring consistency across sessions and enhancing overall accuracy. Equipped with the NDI Polaris Lyra for optical tracking, the Value Edition’s modular system can be tailored to meet the demands of even the most complex TMS research projects. Additional components for novel research applications can be integrated at any time, providing researchers with the flexibility to adapt their experimental designs as their needs evolve.

TMS Research premium technology

TMS Navigator

Premium Edition

The Premium Edition combines the benefits of the Value Edition with enhanced comfort and capabilities offered by the NDI Polaris Vega. Featuring a wider field of view, the Premium Edition simplifies sophisticated experimental setups by offering scientists more space to maneuver around the head. Future-proof your research projects with this edition, designed to support advanced methodologies such as multi-coil setups, navigation in the MRI, and robotic approaches.

TMS navigator MR compatible product

TMS Navigator

MR-Compatible Edition

Leading in advanced research technology, Localite provides high-quality, MR-safe products that allow precise TMS coil navigation within the MRI scanner. The materials have been carefully selected and extensively tested to ensure researchers can safely position TMS coils in the scanner. Enjoy the flexibility of using all familiar software packages during MRI scanning, taking TMS navigation to new heights. Our MR equipment is versatile and can be used both inside and outside the scanner, maximizing flexibility throughout the research process.

Cobot edition TMS Navigator

TMS Navigator

Cobot Edition

In collaboration with our partners at Axilum Robotics, Localite offers an opportunity to fundamentally automate your research protocols. With the robotic Cobot solution, scientists can precisely approach the individual points of the stimulation grid and complete them step by step. The Cobot takes over the coil handling, allowing for seamless execution of complex protocols while fully compensating for head movement.
For studies focusing on depression or neural mapping, the Cobot provides researchers with high-end robotic navigation, delivering unmatched precision and reliability. Inspire fellow scientists and subjects with the Cobot and leave a long-lasting impression on every lab visitor.

Regulatory affairs

In the EU, Localite TMS Navigator products and accessories are CE marked medical devices.

In the U.S., only Localite TMS Navigator TS is FDA-cleared for following intended use:

The TMS Navigator TS helps users to plan, implement and document treatment involving TMS of the brain. The system provides planning and navigation functions using anatomical MR data. Regions of the brain to be stimulated can be determined on the basis of anatomy, functional areas or by entering previously calculated coordinates from brain atlases.

The product is intended for use with the MagVenture therapy systems supplied by Tonica Elektronik A/S (Farum, Denmark), more precisely the R20 and R30 stimulators, the R30 TMS stimulator with MagOption, the X100 stimulator and the X100 stimulator with MagOption only with following magnetic coils: C-100, C-B60, Cool-B65, Cool-B70, Cool D-B80, MC-125, MC-B70, MCF-75, MCF-125, MCF-B65 and MMC-140-II.

Testimonials

Voices about our work

Reliable neuronavigation of the TMS coil, preferably based on individual MRI scans, is a key requirement for state-of-the-art therapeutic approaches. The possibility to further account for functional brain imaging information and personalized electric field simulations brings targeting accuracy to the next level.

Prof. Dr. Til Ole Bergmann | Acting Director NeuroImaging Center (NIC), University of Mainz

Prof. Dr. Til Ole Bergmann

Localite has proven to be an excellent partner in the field of navigated transcranial magnetic stimulation. Their dedication to quality and accuracy is of highest importance for precise and individualized brain stimulation. Our research combines various state-of-the-art brain stimulation and mapping approaches. Localite has been very supportive over the years, accommodating their products to our unique needs.

Prof. Hartwig R. Siebner | Director, Danish Research Centre for Magnetic Resonance, Copenhagen

Prof. Hartwig Siebner

The best in class quality and FDA clearance of Localite’s navigation products instills trust in the SAINT neuronavigation technique.

Christian Gormsen | President and CEO of Magnus Medical, Burlingame

Christian Gormsen

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More to know from Localite

Research Projects

Pushing the boundaries for new approaches

Tms navigator

High end neuronavigation tailored to your demands